| URS with Holmium Laser | URS with Pneumatic Lithotripter |
| Minimal chance of upward migration of stone during treatment | High chance of upward migration of stone during treatment |
| Very effective for soft as well as hard stones | Less effective for hard stones |
| No mucosal injury or bleeding during treatment | Some mucosal injury or bleeding during treatment |
| Reduced need for D J stent | Higher need for D J stent |
| Used with rigid and flexible URS | Used only with rigid URS |